[Journal Article]
Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3
In: European journal of medicinal chemistry, 220, 113500, 2021
[DOI: 10.1016/j.ejmech.2021.113500]

Heine, Viktoria
Hovorková, Michaela
Vlachová, Miluše
Filipová, Marcela
Bumba, Ladislav
et al.

[Journal Article]
Repetitive Synthesis of High-Molecular-Weight Hyaluronic Acid with Immobilized Enzyme Cascades
In: ChemSusChem : chemistry & sustainability, energy & materials, 14, cssc.202101071, 2021
[DOI: 10.1002/cssc.202101071]

Gottschalk, Johannes
Aßmann, Miriam
Kuballa, Jürgen
Elling, Lothar (Corresponding author)

[Journal Article]
Electrochemical Impedance Spectroscopy Biosensor Enabling Kinetic Monitoring of Fucosyltransferase Activity
In: ACS sensors, 6 (3), 1003-1011, 2021
[DOI: 10.1021/acssensors.0c02206]

Heine, Viktoria
Kremers, Tom
Menzel, Nora
Schnakenberg, Uwe (Corresponding author)
Elling, Lothar (Corresponding author)

[Dissertation / PhD Thesis]
Usefulness of glycan-functionalized microgels as lectin scavengers, 2021

Boesveld, Sarah

[Journal Article]
Current state on the enzymatic synthesis of glycosaminoglycans
In: Current opinion in chemical biology, 61, 71-80, 2020
[DOI: 10.1016/j.cbpa.2020.09.008]

Gottschalk, Johannes
Elling, Lothar (Corresponding author)

[Preprint]
Diversity and function of microbial lipases within the mammalian gut, 2020
[DOI: 10.1101/2020.09.08.287425]

Hitch, Thomas C. A.
Masson, Johannes M.
Streidl, Theresa
Fischöder, Thomas
Elling, Lothar
et al.

[Contribution to a conference proceedings, Journal Article]
Synthese des Glykosids 2 (β‐Galaktosyl)‐Ethyl Methacrylat mithilfe einer β Galaktosidase aus Pyrococcus woesei für die Glykopolymersynthese
In: Chemie - Ingenieur - Technik, 92 (9), 1226-1227, 2020
[DOI: 10.1002/cite.202055245]

Wahl, C. (Corresponding author)
Hoffmann, Marius
Gau, E.
Braun, S.
Pich, Andrij
et al.

[Journal Article]
A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity
In: Nature Communications, 11 (1), 6389, 2020
[DOI: 10.1038/s41467-020-19929-w]

Wylensek, David
Hitch, Thomas C. A.
Riedel, Thomas
Afrizal, Afrizal
Kumar, Neeraj
et al.

[Contribution to a book]
Enzymatic Synthesis of Glycans and Glycoconjugates
In: Advances in Biochemical Engineering / Biotechnology, 1-50, 2020
[DOI: 10.1007/10_2020_148]

Rexer, Thomas
Laaf, Dominic
Gottschalk, Johannes
Frohnmeyer, Hannes
Rapp, Erdmann
et al.

[Journal Article]
Sequence‐Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin‐3 and Delay Wound Healing of a Galectin‐3 Positive Tumor Cell Line in an In Vitro Wound Scratch Assay
In: Macromolecular bioscience, 20 (9), 2000163, 2020
[DOI: 10.1002/mabi.202000163]

Freichel, Tanja
Heine, Viktoria
Laaf, Dominic
Mackintosh, Eleanor E.
Sarafova, Sophia
et al.

[Journal Article]
Polyethylene glycol-mediated blocking and monolayer morphology of an electrochemical aptasensor for malaria biomarker detection in human serum
In: Bioelectrochemistry : official journal of the Bioelectrochemical Society, 136, 107589, 2020
[DOI: 10.1016/j.bioelechem.2020.107589]

Figueroa-Miranda, Gabriela
Wu, Changtong
Zhang, Yuting
Nörbel, Lena
Lo, Young
et al.

[Journal Article]
Glycopolymers for Efficient Inhibition of Galectin-3 : In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration
In: Biomacromolecules, 21 (8), 3122-3133, 2020
[DOI: 10.1021/acs.biomac.0c00515]

Filipová, Marcela (Corresponding author)
Bojarová, Pavla (Corresponding author)
Rodrigues Tavares, Marina
Bumba, Ladislav
Elling, Lothar
et al.

[Journal Article]
Synthesis of the Thomsen-Friedenreich-antigen (TF-antigen) and binding of Galectin-3 to TF-antigen presenting neo-glycoproteins
In: Glycoconjugate journal, 37 (4), 457-470, 2020
[DOI: 10.1007/s10719-020-09926-y]

Hoffmann, Marius
Hayes, Marc R.
Pietruszka, Jörg
Elling, Lothar (Corresponding author)

[Journal Article]
Fluorinated Galactoses Inhibit Galactose-1-Phosphate Uridyltransferase and Metabolically Induce Galactosemia-like Phenotypes in HEK-293 Cells
In: Cells, 9 (3), 607, 2020
[DOI: 10.3390/cells9030607]

Janes, Verena
Grabany, Simona
Delbrouck, Julien
Vincent, Stephane P.
Gottschalk, Johannes
et al.

[Dissertation / PhD Thesis]
Entwicklung und Optimierung eines Enzymmodulsystems zur Synthese von Hyaluronsäure, 2020
[DOI: 10.18154/RWTH-2020-04684]

Eisele, Anna

[Dissertation / PhD Thesis]
Investigations on transglycosylation reactions of glycosidases and glycosynthases for the syntheses of (poly-)N-acetyllactosamine glycans, 2020
[DOI: 10.18154/RWTH-2020-03360]

Henze, Manja

[Contribution to a book, Journal Article]
Electrochemical Impedance Spectroscopy Using Interdigitated Gold-Polypyrrole Electrode Combination
In: Physica status solidi / A, 217 (13), 1900827, 2020
[DOI: 10.1002/pssa.201900827]

Kremers, Tom
Menzel, Nora
Freitag, Fabian
Laaf, Dominic
Heine, Viktoria
et al.

[Journal Article]
High-Affinity N -(2-Hydroxypropyl)methacrylamide Copolymers with Tailored N -Acetyllactosamine Presentation Discriminate between Galectins
In: Biomacromolecules, 21 (2), 641-652, 2020
[DOI: 10.1021/acs.biomac.9b01370]

Tavares, Marina Rodrigues
Bláhová, Markéta
Sedláková, Lieselotte
Elling, Lothar
Pelantová, Helena
et al.

[Journal Article]
How bacterial pathogens of the gastrointestinal tract use the mucosal glyco-code to harness mucus and microbiota: New ways to study an ancient bag of tricks
In: International journal of medical microbiology : IJMM, 310 (2), 151392, 2020
[DOI: 10.1016/j.ijmm.2020.151392]

Josenhans, Christine (Corresponding author)
Müthing, Johannes (Corresponding author)
Elling, Lothar (Corresponding author)
Bartfeld, Sina (Corresponding author)
Schmidt, Herbert (Corresponding author)

[Journal Article]
Enzymatic Synthesis of 2-(β-Galactosyl)-ethyl Methacrylate by β-Galactosidase from Pyrococcus woesei and Application for Glycopolymer Synthesis and Lectin Studies
In: Biomacromolecules, 21 (2), 974-987, 2020
[DOI: 10.1021/acs.biomac.9b01647]

Hoffmann, Marius
Gau, Elisabeth
Braun, Susanne
Pich, Andrij (Corresponding author)
Elling, Lothar (Corresponding author)

[Journal Article]
The catabolism of 3,3’-thiodipropionic acid in Variovorax paradoxus strain TBEA6: A proteomic analysis
In: PLOS ONE, 14 (2), e0211876, 2019
[DOI: 10.1371/journal.pone.0211876]

Heine, Viktoria
Meinert-Berning, Christina
Lück, Janina
Mikowsky, Nadine
Voigt, Birgit
et al.

[Contribution to a book, Journal Article]
Key Factors for a One-Pot Enzyme Cascade Synthesis of High Molecular Weight Hyaluronic Acid
In: International journal of molecular sciences, 20 (22), 5664, 2019
[DOI: 10.3390/ijms20225664]

Gottschalk, Johannes
Zaun, Henning
Eisele, Anna
Kuballa, Jürgen
Elling, Lothar (Corresponding author)

[Journal Article]
Enzymatic Cascades for Tailored 13C6 and 15N Enriched Human Milk Oligosaccharides
In: Molecules : a journal of synthetic chemistry and natural product chemistry, 24 (19), 3482, 2019
[DOI: 10.3390/molecules24193482]

Fischöder, Thomas
Cajic, Samanta
Grote, Valerian
Heinzler, Raphael
Reichl, Udo
et al.

[Journal Article]
Identifying Efficient Clostridium difficile Toxin A Binders with a Multivalent Neo-Glycoprotein Glycan Library
In: Bioconjugate chemistry, 30 (9), 2373-2383, 2019
[DOI: 10.1021/acs.bioconjchem.9b00486]

Heine, Viktoria
Boesveld, Sarah
Pelantová, Helena
Křen, Vladimír
Trautwein, Christian
et al.

[Journal Article]
Toward Automated Enzymatic Glycan Synthesis in a Compartmented Flow Microreactor System
In: Journal für praktische Chemie, Chemiker-Zeitung, 361 (19), 4506-4516, 2019
[DOI: 10.1002/adsc.201900709]

Heinzler, Raphael
Fischöder, Thomas
Elling, Lothar (Corresponding author)
Franzreb, Matthias (Corresponding author)

[Journal Article]
Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3
In: RSC Advances, 9 (41), 23484-23497, 2019
[DOI: 10.1039/C9RA05497A]

Freichel, Tanja
Laaf, Dominic
Hoffmann, Miriam
Konietzny, Patrick B.
Heine, Viktoria
et al.

[Journal Article]
Microgels Sopping Up Toxins : GM1a-Functionalized Microgels as Scavengers for Cholera Toxin
In: ACS applied materials & interfaces, 11 (28), 25017-25023, 2019
[DOI: 10.1021/acsami.9b06413]

Boesveld, Sarah
Jans, Alexander
Rommel, Dirk
Bartneck, Matthias
Möller, Martin
et al.

[Journal Article]
Repetitive Batch Mode Facilitates Enzymatic Synthesis of the Nucleotide Sugars UDP‐Gal, UDP‐GlcNAc, and UDP‐GalNAc on a Multi‐Gram Scale
In: Biotechnology journal : BTJ, 14 (4), 1800386, 2018
[DOI: 10.1002/biot.201800386]

Fischöder, Thomas
Wahl, Claudia
Zerhusen, Christian
Elling, Lothar (Corresponding author)

[Journal Article]
Galectin-Carbohydrate Interactions in Biomedicine and Biotechnology
In: Trends in biotechnology, 37 (4), 402-415, 2018
[DOI: 10.1016/j.tibtech.2018.10.001]

Laaf, Dominic
Bojarová, Pavla
Elling, Lothar (Corresponding author)
Kren, Vladimir (Corresponding author)

[Journal Article]
Enzymatic Cascade Synthesis Provides Novel Linear Human Milk Oligosaccharides as Reference Standards for xCGE-LIF Based High-Throughput Analysis
In: Biotechnology journal, 14 (3), 1800305, 2018
[DOI: 10.1002/biot.201800305]

Fischöder, Thomas
Cajic, Samanta
Reichl, Udo
Rapp, Erdmann
Elling, Lothar (Corresponding author)

[Journal Article]
A Compartmented Flow Microreactor System for Automated Optimization of Bioprocesses Applying Immobilized Enzymes
In: Frontiers in Bioengineering and Biotechnology, 6, 189, 2018
[DOI: 10.3389/fbioe.2018.00189]

Heinzler, Raphael
Hübner, Jonas
Fischöder, Thomas
Elling, Lothar
Franzreb, Matthias (Corresponding author)

[Journal Article]
KnowVolution Campaign of an Aryl Sulfotransferase Increases Activity toward Cellobiose
In: Chemistry, 24 (64), 17117-17124, 2018
[DOI: 10.1002/chem.201803729]

Islam, Shohana
Laaf, Dominic
Infanzón, Belén
Pelantová, Helena
Davari, Mehdi D.
et al.

[Journal Article]
High level in vivo mucin-type glycosylation in Escherichia coli
In: Microbial cell factories, 17 (1), 168, 2018
[DOI: 10.1186/s12934-018-1013-9]

Mueller, Phillipp
Gauttam, Rahul
Raab, Nadja
Handrick, René
Wahl, Claudia
et al.

[Journal Article]
Biocompatible glyconanomaterials based on HPMA-copolymer for specific targeting of galectin-3
In: Journal of nanobiotechnology, 16 (1), 73, 2018
[DOI: 10.1186/s12951-018-0399-1]

Bojarová, Pavla (Corresponding author)
Tavares, M. R.
Laaf, Dominic
Bumba, L.
Petrásková, L.
et al.

[Journal Article]
Directed Evolution of Hyaluronic Acid Synthase from Pasteurella multocida towards High-Molecular-Weight Hyaluronic Acid
In: ChemBioChem, 19 (13), 1414-1423, 2018
[DOI: 10.1002/cbic.201800093]

Mandawe, John
Infanzon, Belen
Eisele, Anna
Zaun, Henning
Kuballa, Jürgen
et al.

[Journal Article]
In Vitro One‐Pot Enzymatic Synthesis of Hyaluronic Acid from Sucrose and N‐Acetylglucosamine : Optimization of the Enzyme Module System and Nucleotide Sugar Regeneration
In: ChemCatChem, 10 (14), 2969-2981, 2018
[DOI: 10.1002/cctc.201800370]

Eisele, Anna
Zaun, Henning
Kuballa, Jürgen
Elling, Lothar (Corresponding author)

[Dissertation / PhD Thesis]
DNA methylation changes in hematopoietic development and iPSC-derived model systems, 2018
[DOI: 10.18154/RWTH-2018-226578]

Frobel, Joana

[Journal Article]
Cover Feature: In Vitro One‐Pot Enzymatic Synthesis of Hyaluronic Acid from Sucrose and N‐Acetylglucosamine: Optimization of the Enzyme Module System and Nucleotide Sugar Regeneration (ChemCatChem 14/2018)
In: ChemCatChem, 10 (14), 2924, 2018
[DOI: 10.1002/cctc.201801075]

Eisele, Anna
Zaun, Henning
Kuballa, Jürgen
Elling, Lothar (Corresponding author)

[Dissertation / PhD Thesis]
Design and characterization of galectin-3 fusion proteins and novel multivalent galectin-3 ligands, 2018
[DOI: 10.18154/RWTH-2018-223859]

Böcker, Sophia

[Journal Article]
Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors
In: Bioconjugate chemistry, 29 (4), 1266-1275, 2018
[DOI: 10.1021/acs.bioconjchem.8b00047]

Zhang, Hao
Laaf, Dominic
Elling, Lothar (Corresponding author)
Pieters, Roland J. (Corresponding author)

[Dissertation / PhD Thesis]
Modified multivalent poly-N-acetyllactosamine glycans as novel ligands of human galectin-3, 2018
[DOI: 10.18154/RWTH-2018-00857]

Laaf, Dominic

[Journal Article]
Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling
In: International journal of molecular sciences, 19 (2), 372, 2018
[DOI: 10.3390/ijms19020372]

Bumba, Ladislav
Laaf, Dominic
Spiwok, Vojtěch
Elling, Lothar
Křen, Vladimír
et al.

[Journal Article]
Effective Synthesis of Guanosine 5′‐Diphospho‐β‐l‐galactose Using Bacterial l‐Fucokinase/Guanosine 5′‐Diphosphate‐l‐fucose Pyrophosphorylase
In: Advanced synthesis & catalysis, 359 (23), 4227-4234, 2017
[DOI: 10.1002/adsc.201700901]

Ohashi, Hiroyuki
Wahl, Claudia
Ohashi, Takao
Elling, Lothar (Corresponding author)
Fujiyama, Kazuhito (Corresponding author)

[Journal Article]
Chemo-Enzymatic Synthesis of Branched N -Acetyllactosamine Glycan Oligomers for Galectin-3 Inhibition
In: Advanced synthesis & catalysis, 359 (22), 4015-4024, 2017
[DOI: 10.1002/adsc.201700969]

Laaf, Dominic
Steffens, Hanna
Pelantová, Helena
Bojarová, Pavla
Křen, Vladimír (Corresponding author)
et al.

[Journal Article]
Tailored Multivalent Neo-Glycoproteins: Synthesis, Evaluation, and Application of a Library of Galectin-3-Binding Glycan Ligands
In: Bioconjugate chemistry, 28 (11), 2832-2840, 2017
[DOI: 10.1021/acs.bioconjchem.7b00520]

Laaf, Dominic
Bojarová, Pavla
Pelantová, Helena
Křen, Vladimír (Corresponding author)
Elling, Lothar (Corresponding author)

[Contribution to a book, Journal Article]
Characterization of a new UDP-sugar pyrophosphorylase from Hordeum vulgare (barley)
In: Journal of biotechnology, 258, 51-55, 2017
[DOI: 10.1016/j.jbiotec.2017.03.025]

Wahl, Claudia
Spiertz, Markus
Elling, Lothar (Corresponding author)

[Contribution to a book, Journal Article]
Development of a colourimetric assay for glycosynthases
In: Journal of biotechnology, 257, 162-170, 2017
[DOI: 10.1016/j.jbiotec.2017.02.005]

Hayes, Marc R.
Bochinsky, Kevin A.
Seibt, Lisa S.
Elling, Lothar
Pietruszka, Jörg (Corresponding author)

[Journal Article]
Enzymatic Synthesis of N-Acetyllactosamine (LacNAc) Type 1 Oligomers and Characterization as Multivalent Galectin Ligands
In: Molecules, 22 (8), 1320, 2017
[DOI: 10.3390/molecules22081320]

Fischöder, Thomas
Laaf, Dominic
Dey, Carina
Elling, Lothar (Corresponding author)

[Journal Article]
Biofunctionalized zinc peroxide (ZnO2) nanoparticles as active oxygen sources and antibacterial agents
In: RSC Advances, 7 (62), 38998-39010, 2017
[DOI: 10.1039/C7RA06332F]

Bergs, Christian
Brück, Lisa
Rosencrantz, Ruben R.
Conrads, Georg
Elling, Lothar
et al.

[Contribution to a book, Journal Article]
Two-Step Enzymatic Synthesis of β-d-N-Acetylgalactosamine-(1→4)-d-N-acetylglucosamine (LacdiNAc) Chitooligomers for Deciphering Galectin Binding Behavior
In: Advanced synthesis & catalysis, 359 (12), 2101-2108, 2017
[DOI: 10.1002/adsc.201700331]

Laaf, Dominic
Bojarová, Pavla
Mikulová, Barbora
Pelantová, Helena
Kren, Vladimir (Corresponding author)
et al.