Prof. Dr. Lothar Elling:

ORCID-ID: 0000-0002-3654-0397 Researcher-ID: B-3711-2013 Scopus Author ID: 7004171239



1. L. Elling and M.-R. Kula (1991)
Investigation of the UDP-Glucose dehydrogenase reaction for a coupled assay of UDP-Glucose pyrophosphorylase activities
Biotechnol. Appl. Biochem. 14, 306-316. Pubmed


2. L. Elling, J. E. Ritter and M.-R. Kula (1992)
Characterization of the auxiliary enzymes for the assay of β-1,4-galactosyltransferase
DECHEMA Biotechnology Conferences Vol. 5 Part A, 141-144.

3. L. Elling, S. Neumann and M.-R. Kula (1992)
Isolation and characterization of UDP-Glucose pyrophosphorylase from flax
DECHEMA Biotechnology Conferences Vol. 5 Part A, 145-146.


4. L. Elling and M.-R. Kula (1993)
Purification of sucrose synthase from rice and its protein-chemical characterization
J. Biotechnology 29, 277-286. ScienceDirect

5. L. Elling, M. Grothus and M.-R. Kula (1993)
Investigation of sucrose synthase from rice for the synthesis of various nucleotide sugars and saccharides
Glycobiology 3, 349-355. Glycobiology

6. J. Peters, H.-P. Brockamp, T. Minuth, M. Grothus, Alois Steigel, Maria-Regina Kula and Lothar Elling (1993)
Combined Chemoenzymatic Synthesis of 2-O-6-Deoxy-α-L-Sorbofuranosyl-D-Glucose
Tetrahedron: Asymmetry 4, 1173-1182. ScienceDirect


7. A. Zervosen, L. Elling and M.-R. Kula (1994)
Continuous Enzymatic Synthesis of 2´Deoxythymidine-5´-α-D-glucopyranosyl)diphosphate
Angew. Chem. Int. Ed. Engl. 33, 571-572. Wiley

8. M. Grothus, A. Steigel, M.-R. Kula and L. Elling (1994)
Enzymatic Synthesis of α-D-Glucopyranosyl-α-D-Lyxopyranoside and α-D-Glucopyranosyl-β-D- Xylulofuranoside.
Carbohydrate Letters 1, 83-88.

9. L. Elling and M.-R. Kula (1994)
Purification of UDP-glucose pyrophosphorylase from germinated barley (malt)
J. Biotechnol. 34, 157-163. ScienceDirect


10. L. Elling, M. Grothus, A. Zervosen and M.-R. Kula (1995)
Application of Sucrose Synthase from Rice Grains for the Synthesis of Carbohydrates
Enzyme Engineering XII (eds.: M.-D. Legoy and D. Thomas), Annals of the New York Academy of Sciences Vol. 750, 329-331. The NewYork Academy of Science

11. L. Elling, M. Grothus, A. Zervosen, M. Péus, A. Helfer, A. Stein, H. Adrian and M.-R. Kula (1995)
Isolation of sucrose synthase from rice grains (Oryza sativa) in pilot scale for application in carbohydrate synthesis
Biotechnol. Appl. Biochem. 21, 29-37.

12. L. Elling (1995)
Effect of metal ions on sucrose synthase from rice grains - a study on enzyme inhibition and enzyme topography
Glycobiology 5, 201-206. Glycobiology

13. L. Elling and M.-R. Kula (1995)
Characterization of sucrose synthase from rice grains for the enzymatic synthesis of UDP- and TDP-Glucose
Enzyme Microb.Technol. 17, 929-934. ScienceDirect

14. G.F. Herrmann, L. Elling, C.H. Krezdorn, R. Kleene, E.G. Berger and C. Wandrey (1995)
Use of Transformed Whole Yeast Cells Expressing β-1,4-Galactosyltransferase for the Synthesis of N- Acetyllactosamine
Bioorganic & Medicinal Chemistry Letters 5, 673-676. ScienceDirect

15. A. Stein, M.-R. Kula, L. Elling, S. Verseck und W. Klaffke (1995)
Synthesen von dTDP-6-Desoxy-4-ketoglucose und deren Analoga mit nativer und rekombinanter dTDP-Glucose-4,6- Dehydratase
Angew. Chemie 107, 1881-1883. Wiley

16. A. Stein, M.-R. Kula, L. Elling, S. Verseck and W. Klaffke (1995)
Synthesis of dTDP-6-Deoxy-4-ketoglucose and Analogues with Native and Recombinant dTDP-Glucose-4,6-dehydratase
Angew. Chemie Int. Ed. Engl. 34, 1748-1749. Wiley


17. J.E. Ritter, C. Berlin and L. Elling (1996)
A continuous microtiter plate assay for screening nucleotide sugar synthesizing nucleotidyltransferases
Anal. Biochem. 234, 74-82. ScienceDirect

18. A. Zervosen and L. Elling (1996)
A Novel Three-Enzyme-Reaction-Cycle for the Synthesis of N-Acetyllactosamine with in Situ Regeneration of Uridine 5´-Diphosphate Glucose and Uridine 5´-Diphosphate Galactose
J. Am. Chem. Soc. 118, 1836-1840. ACS Publications

19. A. Zervosen, A. Stein, H. Adrian and L. Elling (1996)
Combined Enzymatic Synthesis of Nucleotide (Deoxy)sugars from Sucrose and Nucleoside monophosphates
Tetrahedron52, 2395-2404. ScienceDirect

20. C.H. Hokke, A. Zervosen, L. Elling, D.H. Joziasse and D.H. Van Den Eijnden (1996)
One-pot enzymatic synthesis of the Galα1-3Galβ1-4GlcNAc sequence with in situ UDP-Gal regeneration
Glycoconjugate J. 13, 687-692. SpringerLink

21. L. Elling (1996)
Kinetic characterization of UDP-glucose pyrophosphorylase from germinated barley (malt)
Phytochemistry42, 955-960. ScienceDirect

22. L. Elling, J.E. Ritter and S. Verseck (1996)
Expression, purification and characterization of recombinant Phosphomannomutase and GDP-α-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-α-D-mannose from D-mannose.
Glycobiology 6, 591-597. Glycobiology


23. L. Elling (1997)
Glycobiotechnology: Enzymes for the Synthesis of Nucleotide Sugars.
Adv. Biochem. Eng. Biotechnol. 58, 89-144. SpringerLink

24. T. Bülter, C. Wandrey and L. Elling (1997)
Chemo-enzymatic synthesis of UDP-N-acetyl-α-D-galactosamine
Carbohydr. Res. 305, 469-473. ScienceDirect

25. S. Fey, L. Elling and U. Kragl (1997)
The cofactor Mg2+ - a key switch for effective continuous enzymatic production of GDP-mannose using recombinant GDP-mannose pyrophosphorylase
Carbohydr. Res. 305, 475-481. ScienceDirect


26. A. Stein, M.-R. Kula and L. Elling (1998)
Combined preparative enzymatic synthesis of dTDP-6-deoxy-4-keto-D-glucose from dTDP and sucrose.
Glycoconjugate J. 15, 139-145. SpringerLink

27. A. Zervosen, U. Römer and L. Elling (1998)
Application of recombinant sucrose synthase - Large scale synthesis of ADP-glucose
Journal of Molecular Catalysis B: Enzymatic 5, 25-28. ScienceDirect


28. A. Zervosen and L. Elling (1999)
Application of Sucrose Synthase in the Synthesis of Nucleotide Sugars and Saccharides.
In: Methods in Biotechnology, Vol. 10: Carbohydrate Biotechnology Protocols (C. Bucke, ed.), Humana Press Inc., Totowa, New Jersey, 235-254. ScienceDirect

29. T. Bülter and L.Elling (1999)
Enzymatic Synthesis of Nucleotide Sugars
Glycoconjugate J. 16, 147-159. SpringerLink

30. L. Elling (1999)
Enzymatic Tools for the Synthesis of Nucleotide (Deoxy)sugars
In: Bioorganic Chemistry - Highlights and New Aspects (U. Diederichsen, Th.K. Lindhorst, B. Westermann, L. Wessjohann, Eds.), Wiley-VCH, Weinheim, 166-171. Ub

31. L. Elling, A. Zervosen, R. Gutiérrez Gallego, V. Nieder, M. Malissard, E.G. Berger, J.F.G. Vliegenthart and J.P. Kamerling (1999)
UDP-N-Acetyl-a-D-glucosamine as acceptor substrate of β-1,4-galactosyltransferase.
Enzymatic synthesis of UDP-N-acetyllactosamine
Glycoconjugate J. 16, 327-336. SpringerLink


32. T. Bülter and L. Elling (2000)
Enzymatic Synthesis of UDP-Galactose on a Gram Scale
Journal of Molecular Catalysis B: Enzymatic 8, 281-284. ScienceDirect

33. G.M. Watt, S.L. Flitsch, S. Fey, L. Elling,and U. Kragl (2000)
The preparation of deoxy derivatives of mannose-1-phosphate and their substrate specificity towards recombinant GDP-mannose pyrophosphorylase from Salmonella enterica, group B
Tetrahedron Asymmetry, 11, 621-628. ScienceDirect


34. A. Zervosen, V. Nieder, R. Gutiérrez Gallego, J.P. Kamerling, J.F.G. Vliegenthart, L. Elling (2001)
Synthesis of nucleotide-activated oligosaccharides by β-galactosidase from Bacillus circulans
Biol. Chem., 382, 299-311. de Gruyter

35. U. Römer, N. Nettelstroth, W. Köckenberger, and L. Elling (2001)
Characterization of recombinant sucrose synthase 1 from potato for the synthesis of sucrose analogues
Adv. Synth. Catal., 343, 655-661. Wiley

36. S. Amann, G. Dräger, C. Rupprath, A. Kirschning and L. Elling (2001)
(Chemo)enzymatic Synthesis of dTDP-activated 2,6-Dideoxysugars as Building Blocks of Polyketide Antibiotics
Carbohydr. Res., 335, 23-32. ScienceDirect

37. T. Bülter, T. Schumacher, D.-J. Namdjou, R. Guitierrez Gallego, H. Clausen, and L. Elling (2001)
Chemo-enzymatic Synthesis of biotinylated Nucleotide Sugars as Substrates for Glycosyltransferases
ChemBioChem, 2, 884-894. ChemistryEurope

38. N. Brinkmann, M. Malissard, M. Ramuz, U. Römer, T. Schumacher, E.G. Berger, L. Elling, C. Wandrey, and A. Liese (2001)
Chemo-enzymatic Synthesis of the Galili Epitope Galα(1->3)Galβ(1->4)GlcNAc on a Homogeneously Soluble PEG Polymer by a Multi-Enzyme System
Bioorg. Med. Chem. Lett., 11, 2503-2506. ScienceDirect


39. A.K. Sinha, M.G. Hofmann, U. Römer, W. Köckenberger, L. Elling and T. Roitsch (2002)
Metabolizable and Non-Metabolizable Sugars Activate Different Signal Transduction Pathways in Tomato
Plant Physiol., 128, 1480-1489. Pubmed Central

40. V. Nieder, S.P. Marx, R. Gutierrez Gallego, J.P. Kamerling, J.F.G. Vliegenhart, and L. Elling (2002)
Synthesis of nucleotide-activated disaccharides with β-Galacosidase from Bacillus circulans and α-Galactosidase from Bifidobacterium adolescentis
J. Mol. Catal. B: Enzymatic, 21, 157-166. ScienceDirect


41. U. Römer, C. Rupprath and L. Elling (2003)
The Donor Substrate Spectrum of Recombinant Sucrose Synthase 1 from Potato for the Synthesis of Sucrose Analogues
Adv. Synth. Catal., 345, 684-686. Wiley


42. U. Römer, H. Schrader, N. Günther, N. Nettelstroth, W.B. Frommer, and L. Elling (2004)
Expression, purification and characterization of recombinant sucrose synthase 1 from Solanum tuberosum L. for carbohydrate engineering
Journal of Biotechnology, 107, 135-149. ScienceDirect

43. V. Nieder, M. Kutzer, V. Kren, R. Gutiérrez Gallego, J. P. Kamerling, and L. Elling (2004)
Screening and Characterization of β-N-Acetylhexosaminidases for the Synthesis of Nucleotide-Activated Disaccharides
Enzyme Microb. Technol., 34, 407-414. ScienceDirect

44. A. Rentmeister, C. Hoh, S. Weidner, G. Dräger, L. Elling, A. Liese, C. Wandrey (2004)
Kinetic examination and simulation of GDP-β-L-fucose synthetase reaction using NADPH or NADH
Biocatal. Biotrans., 22, 49-56. Taylor & Frances


45. C. Rupprath, T. Schumacher and L. Elling (2005)
Nucleotide Deoxysugars: Essential Tools for the Glycosylation Engineering of Novel Bioactive Compounds
Curr. Med. Chem., 12 (14), 1637-1675. BenthamScience Publishers LTD.

46. L. Elling, C. Rupprath , N. Günther, U. Römer, S. Verseck, P. Weingarten, G. Dräger, A. Kirschning, and W. Piepersberg (2005)
An Enzyme Module System for the Synthesis of dTDP-activated Deoxysugars from dTMP and Sucrose
ChemBioChem 6, 1423-1430. Wiley

47. P. Fialová, D.-J. Namdjou, R. Ettrich,V. Prikrylová, J. Rauvolfová, K. Krenek, M. Kuzma, L. Elling, K. Bezouška, and V. Kren (2005)
Combined Application of Galactose Oxidase and b-N-Acetylhexosaminidase in the Synthesis of Complex Immunoactive N-Acetyl-D-galactosaminides
Adv. Synth. Catal., 347, 997-1006. Wiley


48. D.-J. Namdjou, B. Sauerzapfe, J. Schmiedel, G. Dräger, S. Bernatchez, W. Wakarchuk, and L. Elling (2007)
Combination of UDP-Glc(NAc) 4´-Epimerase and Galactose Oxidase in a One-Pot Synthesis of Biotinylated Nucleotide Sugars
Adv. Synth. Catal., 349, 314-318. Wiley

49. C. Rupprath, M. Kopp, D. Hirtz, R. Müller, and L. Elling (2007)
An Enzyme Module System for in situ Regeneration of dTDP-activated deoxysugars
Adv. Synth. Catal., 349, 1489-1496. Wiley

50. M. Kopp, C. Rupprath, H. Irschik ,L. Elling, and R. Müller (2007)
SorF, a glycosyltransferase with promiscuous donor substrate specificity in vitro
ChemBioChem, 8, 813-819. Wiley

51. L. Elling (2007)
Exploring and broadening the biocatalytic properties of recombinant sucrose synthase 1 for the synthesis of sucrose analogs
Asymmetric Synthesis with Chemical and Biological Methods, 376. Wiley


52. B. Sauerzapfe, D.-J. Namdjou, T. Schumacher, N. Linden, K.Krenek, V. Kren and L. Elling (2008)
Characterization of recombinant fusion constructs of human beta 1,4-galactosyltransferase 1 and the lipase pro-peptide from Staphylococcus hyicus
J. Mol. Cat. B-Enzymatic, 50, 128-140. ScienceDirect

53. P. Bojarová, K. Krenek, M. Kuzma, L. Petrasková, K. Bezouska, D.-J. Namdjou, L. Elling and V. Kren (2008)
N-acetylhexosamine triad in one molecule: Chemoenzymatic introduction of 2-acetamido-2-deoxy-beta-D- galactopyranosyluronic acid residue into a complex oligosaccharide
J. Mol. Cat. B-Enzymatic, 50, 69-73. ScienceDirect

54. B. Sauerzapfe, L. Engels and L. Elling (2008)
Broadening the biocatalytic properties of recombinant sucrose synthase 1 from potato (Solanum tuberosum L.) by expression in Escherichia coli and Saccharomyces cerevisiae
Enzyme and Microbial Technol., 43, 289-296. ScienceDirect

55. B. Sauerzapfe and L. Elling (2008)
Multi-enzyme systems for the synthesis of glycoconjugates
Multi-Step Enzyme Catalysis, 83-107. Wiley


56. P. Bojarová, K. Krenek, K. Wetjen, K. Adamiak, H. Pelantová, K. Bezouska, L. Elling and V. Kren (2009)
Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase - way to new glycodrugs and materials
Glycobiology, 19, 509-517. Glycobiology

57. B. Sauerzapfe, K. Krenek, J. Schmiedel, W.W. Wakarchuk, H. Pelantová, V. Kren and L. Elling (2009)
Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces.
Glycoconj J., 26, 141-159. SpringerLink

58. L. Engels, H. Klose and L. Elling (2009)
In-vitro-Synthese der UDP-Glucuronsäure und des Glycan-Epitops HNK1 mit einem hochflexiblen Enzym-Modul-System
Chemie Ingenier Technik, 81, 1258-1259. Wiley


59. L. Engels, P. Babczyk and L. Elling (2010)
Kombinatorische Biokatalyse zur In-vitro-Synthese von UDP-Glucuronsäure
Chemie Ingenieur Technik, 82, 1526. Wiley

60. C. Römer, C. Rech and L. Elling (2010)
Modifikation von Poly-LacNAc-Strukturen zur Funktionalisierung von Biomaterialien
Chemie Ingenieur Technik, 82, 1535. Wiley


61. K. Witten, C. Rech, T. Eckert, S. Charrak, W. Richtering, L. Elling and U. Simon (2011)
Glyco-DNA-Gold Nanoparticles: Lectin-Mediated Assembly and Dual-Stimuli Response
Small, 7, 1954-1960. Wiley

62. T. Anders, K. Adamiak, H. Keul, L. Elling and M. Möller (2011)
Synthesis of a Difunctional Orthogonal Coupler for the Preparation of Carbohydrate-Functionalized sP(EO-stat-PO) Hydrogels
Macromol. Biosci.,11, 1201-1210. Wiley

63. A. Drozdová, P. Bojarová, K. Krenek, L. Weignerová, B. Henßen, L. Elling, H. Christensen, H. Jensen, H. Pelantová, M. Kuzma K. Bezouska, M. Krupová, D. Adamek, K. Slámová and V. Kren (2011)
Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors
Carbohydr. Res.,346, 1599-1609. ScienceDirect

64. C. Rech, R. Rosencrantz, K. Krenek, H. Pelantová, P. Bojarová, C. Römer, F.-G. Hanisch, V. Kren and L. Elling (2011)
Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir- Glycosyltransferases
Adv. Syn. Cat., 353, 2492-2500. Wiley

65. C. Römer and L. Elling (2011)
Galectins: Structures, Binding Properties and Function in Cell Adhesion
Biomaterials - Physics and Chemistry, 3-28. Intech

66. L. Engels and L .Elling (2011)
Enzymatic and Chemoenzymatic Synthesis of Nucleotide Sugars: Novel Enzymes, Novel Substrates, Novel Products, and Novel Routes
Carbohydrate-Modifying Biocatalysts, 237-255. Taylor & Francis


67. M. Beer, C. Rech, S. Diederichs, K. Hahn, K. Bruellhoff, M. Möller, L. Elling and J. Groll (2012)
A hydrogel-based versatile screening platform for specific biomolecular recognition in a well plate format
Anal. Bioanal. Chem., 403, 517-526. SpringerLink

68. K. Adamiak, T. Anders, M. Henze, H. Keul, M. Möller and L. Elling (2012)
Chemo-Enzymatic synthesis of functionalized oligomers of N-Acetyllactosamine glycan derivatives and their immobilization on biomaterial surfaces
J. Mol. Catal. B: Enzymatic, 84, 108-114. ScienceDirect

69. C. Kamerke, M. Pattky, Carolin Huhn and L .Elling (2012)
Synthesis of UDP-activated oligosaccharides with commercial β-galactosidase from Bacillus circulans under microwave irradiation
J. Mol. Catal. B: Enzymatic, 79, 27-34. ScienceDirect

70. C. Kupper, R. Rosencrantz, B. Henßen, H. Pelantová, S. Thönes, A. Drozdová, V. Kren and L. Elling (2012) Chemo-enzymatic modification of poly-N-acetylactosamine (LacNAc) oligomers and N,N- diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment
Beilstein J. Org. Chem., 8, 712-725. Beilstein Journal

71. M. Hdenius, T. Hieronymus, M. Zenke, C. Becker, L. Elling, J. Bornemann, J. Wong, W. Richtering, U. Himmelreich and M. De Cuyper (2012)
Magnetically triggered clustering of biotinylated iron oxide nanoparticles in the presence of streptavidinylated enzymes
Nanotechnology, 23, 355707. IOPScience


72. M. Beer, C. Rech, P. Gasteier, B. Sauerzapfe, J. Salber, A. Ewald, M. Möller, L. Elling and J. Groll (2013)
The next step in biomimetic material design: poly-LacNAc-mediated reversible exposure of extra cellular matrix components
Adv. Healthc. Mater., 2, 306-311. Wiley

73. P. Borjarová, R. Rosencrantz, L. Elling and V. Kren (2013)
Enzymatic glycosylation of multivalent scaffolds
Chem. Soc. Rev., 42, 4774-4797. Royal Society of Chemistry

74. K. Witten, J. Ruff, A. Mohr, D. Görtz, T. Recker, N. Rinis, C. Rech, L. Elling, G. Müller-Newen and U. Simon (2013)
Cellular uptake of fluorophore-labeled glyco-DNA-gold nanoparticles
J. Nanopart. Res., 15, 1992-2003. SpringerLink

75. C. Kupper, S. Böcker, H. Liu, C. Adamczyk, J. van de Kamp, T. Recker, B. Lethaus, W. Jahnen-Dechent, S. Neuss, G. Müller-Newen and L. Elling 2013)
Fluorescent SNAP-tag galectin fusion proteins as novel tolls in glycobiology
Curr. Pharm. Des., 19, 5457-5467. IngentaConnect

76. K. Purtchartová, L. Engels, P. Marthol, M. Sulc, M. Kuzma, K. Slámová, L. Elling and V. Kren (2013)
Enzymatic preparation of silybin phase II metabolites: sulfation using aryl sulfotransferase from rat liver
Appl. Microbiol. Biotechnol., 97, 10391-10398. SpringerLink


77. L. Engels and L. Elling (2014)
WbgL: a novel bacterial α-1,2-fucosyltransferase for the synthesis of 2'-fucosyllactose
Glycobiology, 24, 170-178. Glycobioloy

78. M. Henze, D.J. You, C. Kamerke, N. Hoffmann, C. Angkawidjaja, S. Ernst, J. Pietruszka, S. Kanaya and L. Elling (2014)
Rational design of a glycosynthase by the crystal structure of β-Galactosidase from Bacillus ciculans ( BgaC) and its use for the synthesis of N-acetyllactosamine type 1 glycan structures
J. Biotechnol., 10, 78-85. ScienceDirect


79. H. Park, R.R. Rosencrantz, L. Elling and A. Böker (2015)
Glycopolymer Brushes for Specific Lectin Binding by Controlled Multivalent Presentation of N- Acetyllactosamine Glycan Oligomers
Macromol. Rapid Commun., 36(1), 45-54. Wiley

80. S. Böcker, D. Laaf and L. Elling (2015)
Galectin Binding to Neo-Glycoproteins: LacDiNAC Conjugated BSA as Ligand for Human Galectin-3
Biomolecules, 5(3), 1671-1696. Biomolecules

81. M. Henze, S. Schmidtke, N. Hoffmann, H. Steffens, J. Pietruska and L. Elling (2015)
Combination of Glycosyltransferases and Glycosynthase in Sequential and One-Pot Reactions for the Synthesis of Type1 and Type2 N-Acetyllactosamine Oligomers
ChemCatChem, 7(19), 3131-3139. Wiley

82. J. Lazar, H. Park, R.R. Rosencrantz, A. Böker, L. Elling and U. Schnakenberg (2015)
Evaluating the Thickness of Multivalent Glycopolymer Brushes for Lectin Binding
Macromol. Rapid Commun., 36(16), 1472-1478. Wiley

83. L. Engels, M. Henze, W. Hummel and L. Elling (2015)
Enzyme Module Systems for the Synthesis of Uridine 5´-Diphospho-alpha-D-glucuronic Acid and Non-Sulfated Human Natural Killer Cell-1 (HNK-1) Epitope
Adv. Syn. Cat., 357(8), 1751-1762. Wiley


84. H. Park, S. Walta, R.R. Rosencrantz, A. Korner, C. Schulte, L. Elling, W. Richtering and A. Böker (2016)
Micelles from sel-assembled double-hydrophilic PHEMA-glycopolymer-diblock copolymers as multivalent scaffolds for lectin binding
Polymer Chem., 7(4), 878-886. Royal Society of Chemistry

85. M. Henze, D. Merker and L. Elling (2016)
Microwave-Assisted Synthesis of Glycoconjugates by Transgalactosylation with Recombinant Thermostable β-Glycosidase from Pyrococcus
Int. J. Mol. Sci., 17(2), 210. IJMS

86. B. Lange, A. Simonova, T. Fischöder, H. Pelantova, V. Kren and L. Elling (2016)
Towards Keratan Sulfate - Chemoenzymatic Cascade Synthesis of Sulfated N-Acetyllactosamine (LacNac) Glycan Oligomers
Adv. Syn. Cat., 358(4), 584-596. Wiley

87. R.R. Rosencrantz, V.H. Nguyen, H. Park, C. Schulte, A. Böker, U. Schnakenberg and L. Elling (2016)
Lectin binding studies on a glycopolymer brush flow-trough biosensor by localized surface plasmon resonance
Anal. Bioanal. Chem., 408(20), 5633-5640. SpringerLink

88. C. Wahl, D. Hirtz and L. Elling (2016)
Multiplexed Capillary Electrophoresis as Analytical Tool for Fast Optimization of multi-Enzyme Cascade Reactions - Synthesis of Nucleotide Sugars: Dedicated to Prof. Vladimír Kren on the occasion of his 60th birthday Wiley

89. J. Lazar, R.R. Rosencrantz, L.Elling and U. Schnakenberg (2016)
Simultaneous Electrochemical Impedance Spectroscopy and Localized Surface Plasmon Resonance in a Microfluidic Chip: New Insights into the Spatial Origin of the Signal
Anal. Chem., 88(19), 9590-9596. ACS Publications


90. S. Böcker and L. Elling (2017)
Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3
Bioengineering, 4(2). MDPI

91. S. Böcker and L. Elling (2017)
Binding characteristics of galectin-3 fusion proteins
Glycobiology, 27(5). Glycobiology

92. A. Jans, R.R. Rosencrantz, A. Mandic, N. Anwar, S. Boesveld, C. Trautwein, M. Moeller, G. Sellge, L. Elling and A. Kühne (2017)
Glycan-Functionalized Microgels for Scavenging and Specific Binding of Lectins
Biomacromolecules, 18(5), 1460-1465. ACS Publications

93. D. Laaf, P. Bojarová, B. Mikulová, H. Pelantová, V. Křen and L. Elling (2017)
Two-Step Enzymatic Synthesis of β-d-N-Actylgalactosamine-(1-4)-d-N-actylglucosamine (LacdiNAc) Chitooligomers for Deciphering Galectin Binding Behavior
Adv. Synth. Catal., 359(12), 2101-2108. Wiley

94. C. Bergs, L. Brück, R.R. Rosencrantz, G. Conrads, L. Elling and A. Pich (2017)
Biofunctionalized zinc peroxide (ZnO2) nanoparticles as active oxygen sources and antibacterial agents
RSC Advances, 7(62), 38998-39010. Royal Society of Chemistry

95. T. Fischöder, D. Laaf, C. Dey and L. Elling (2017)
Enzymatic Synthesis of N-Acetyllactosamine (LacNAc) Type 1 Oligomers and Characterization as Multivalent Galectin Ligands
Molecules, 22(8), 1320-. MDPI

96. M. Hayes, K Bochinsky, L. Seibt, L. Elling and J. Pietruszka (2017)
Development of a colourimetric assay for glycosynthases
J. Biotechnol., 257, 162-170. ScienceDirect

97. C. Wahl, M. Spiertz and L. Elling (2017)
Characterization of a new UDP-sugar pyrophosphorylase from Hordeum vulgare (barley)
J. Biotechnol., 258, 51-55. ScienceDirect

98. D. Laaf, P. Bojarová, H. Pelantová, V. Křen and L. Elling (2017)
Tailored Multivalent Neo-Glycoproteins: Synthesis, Evaluation, and Application of a Library of Galectin-3-Binding Glycan Ligands
Bioconj.Chem., 28(11), 2832-2840. ACS Publications

99. D. Laaf, H. Steffens, P. Bojarová, H. Pelantová, V. Křen and L. Elling (2017)
Chemo-Enzymatic Synthesis of Branched N-Acetyllactosamine Glycan Oligomers for Galectin-3 Inhibition
Adv. Synth. Catal., 359(22), 4015-4024. Wiley

100. H. Ohashi, C. Wahl, T. Ohashi, L.Elling and K. Fujiyama (2017)
Effective Synthesis of Guanosine 5′-Diphospho-β- l -galactose Using Bacterial l -Fucokinase/Guanosine 5′-Diphosphate- l -fucose Pyrophosphorylase
Adv. Syn. Cat., 359(23), 4227-4234. Wiley


101. L. Bumba, V. K řen, L. Elling, D. Laaf, P Bojarov á and V. Spiwok (2018)
Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling
Int. J. Mol. Sci., 19(2), 372-. MDPI

102. H. Zhang, D. Laaf, L. Elling and R. Pieters (2018)
Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors
Bioconj. Chem., 29(4), 1266-1275. ACS Publications

103. A. Eisele, H. Zaun, J. Kuballa and L. Elling (2018)
In Vitro One‐Pot Enzymatic Synthesis of Hyaluronic Acid from Sucrose and N‐Acetylglucosamine : Optimization of the Enzyme Module System and Nucleotide Sugar Regeneration
ChemCatChem, 10(14), 2969-2981. Wiley

104. J. Mandawe, B. Infanzon, A. Eisele, H. Zaun, J. Kuballa et al. (2018)
Directed Evolution of Hyaluronic Acid Synthase from Pasteurella multocida towards High-Molecular-Weight Hyaluronic Acid
ChemBioChem, 10(14), 2969-2981. Wiley

105. P. Bojarová, M. Tavares, D. Laaf, L. Bumba, L. Petrásková, et al. (2018)
Biocompatible glyconanomaterials based on HPMA-copolymer for specific targeting of galectin-3
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106. P. Mueller, R. Gauttam, N. Raab, R. Handrick, C. Wahl, et al. (2018)
High level in vivo mucin-type glycosylation in Escherichia coli
Microb. Cell Fact., 17(1), 168. BMC

107. S. Islam, D. Laaf, B. Infanzon, H. Pelantová, M. Davari, et al. (2018)
KnowVolution Campaign of an Aryl Sulfotransferase Increases Activity toward Cellobiose
Chemistry, 24(64), 17117-17124. Wiley

108. R. Heinzler, J. Hübner, T. Fischöder, L. Elling, M. Franzreb (2018)
A Compartmented Flow Microreactor System for Automated Optimization of Bioprocesses Applying Immobilized Enzymes
Front. Bioeng. Biotechnol., 6, 189. Frontiers


109. D. Laaf, P. Bojarova, L. Elling, V. Kren (2019)
Galectin-Carbohydrate Interactions in Biomedicine and Biotechnology
Trends Biotechnol., 37 (4), 402-415. ScienceDirect

110. T. Fischöder, C. Wahl, C. Zerhusen, L. Elling (2019)
Repetitive Batch Mode Facilitates Enzymatic Synthesis of the Nucleotide Sugars UDP-Gal, UDP-GlcNAc, and UDP-GalNAc on a Multi-Gram Scale
Biotechnol J 14, 4 Wiley

111. T. Fischöder, S. Cajic, U. Reichl, E. Rapp, L. Elling (2019)
Enzymatic Cascade Synthesis Provides Novel Linear Human Milk Oligosaccharides as Reference Standards for xCGE-LIF Based High-Throughput Analysis
Biotechnol. J. 14, 3 Wiley

112. T. Fischöder, S. Cajic, V. Grote, R. Heinzler, U. Reichl, M. Franzreb, E. Rapp, L. Elling (2019)
Enzymatic Cascades for Tailored 13C6 and 15N Enriched Human Milk Oligosaccharides
Molecules 24, 19, 3482 MDPI

113. J. Gottschalk, H. Zaun, A. Eisele, J. Kuballa, L. Elling (2019)
Key Factors for A One-Pot Enzyme Cascade Synthesis of High Molecular Weight Hyaluronic Acid
Internat. J. Mol. Sci. 20, 5664 MDPI

114. R. Heinzler, T. Fischöder, L. Elling, M. Franzreb (2019)
Toward Automated Enzymatic Glycan Synthesis in a Compartment Flow Microreactor System
Adv. Synth. Catal. 361, 4506-4516 Wiley

115. V. Heine, S. Boesveld, H. Pelantová, V. Křen, C. Trautwein, P. Strnad, L. Elling (2019)
Identifying Efficient Clostridium difficile Toxin A Binders with a Multivalent Neo-Glycoprotein Glycan Library
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116. T. Freichel, D. Laaf, M. Hoffmann, P. B. Konietzny, V. Heine, R. Wawrzinek, C. Rademacher, N. L. Snyder, L. Elling, L. Hartmann (2019)
Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3
RSC Advances 9, 23484-23497 Royal society of Chemistry

117. S. Boesveld, A. Jans, D. Rommel, M. Bartneck, M. Moller, L. Elling, C. Trautwein, P. Strnad, A. J. C. Kuehne (2019)
Microgels Sopping Up Toxins-GM1a-Functionalized Microgels as Scavengers for Cholera Toxin
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118. T. Rexer, D. Laaf, J. Gottschalk, H. Frohnmeyer, E. Rapp et al. (2020)
Enzymatic Synthesis of Glycans and Glycoconjugates
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119. J. Gottschalk, L. Elling (2020)
Current state on the enzymatic synthesis of glycosaminoglycans
Curr. Opin. Chem. Biol., 61, 71-80 ScienceDirect

120. T. Hitch, J. Masson, T. Streidel, T. Fischöder, L. Elling (2020)
Diversity and function of microbial lipases within the mammalian gut
bioRxiv CSH

121. C. Wahl, M. Hoffmann, E. Gau, S. Braun, A. Pich et al. (2020)
Synthese des Glykosids 2 (β‐Galaktosyl)‐Ethyl Methacrylat mithilfe einer β Galaktosidase aus Pyrococcus woesei für die Glykopolymersynthese
Chem. Ing. Tech., 92, 9, 1226-1227 Wiley

122. D. Wylensek, T. Hitch, T. Riedel , A. Afrizal, N. Kumar et al. (2020)
A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity
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123. T. Freichel, V. Heine, D. Laaf, E. Mackintosh, S. Sarafova et al. (2020)
Sequence‐Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin‐3 and Delay Wound Healing of a Galectin‐3 Positive Tumor Cell Line in an In Vitro Wound Scratch Assay
Macromol. Biosci., 20, 9, 2000163 Wiley

124. G. Figueroa, C. Wu, Y. Zhang, L. Nörbel, Y. Lo et al. (2020)
Polyethylene glycol-mediated blocking and monolayer morphology of an electrochemical aptasensor for malaria biomarker detection in human serum
Bioelectrochem., 136, 107589 ScienceDirect

125. M. Filipová, P. Bojarová, M. Rodrigues Tavares, L. Bumba, L. Elling (2020)
Glycopolymers for Efficient Inhibition of Galectin-3 : In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration
Biomacromol., 21, 8, 3122-3133 ACS Publications

126. M. Hoffmann, M. Hayes, J. Pietruzka, L. Elling (2020)
Synthesis of the Thomsen-Friedenreich-antigen (TF-antigen) and binding of Galectin-3 to TF-antigen presenting neo-glycoproteins
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127. V. Janes, S. Grabany, J. Delbrouck, S. Vincent, J. Gottschalk (2020)
Fluorinated Galactoses Inhibit Galactose-1-Phosphate Uridyltransferase and Metabolically Induce Galactosemia-like Phenotypes in HEK-293 Cells
Cells, 9, 3, 607 MDPI

128. T. Kremers, N. Menzel, F. Freitag, D. Laaf, V. Heine, L. Elling and U. Schnakenberg (2020)
Electrochemical Impedance Spectroscopy Using Interdigitated Gold-Polypyrrole Electrode Combination
Phys Status Solidi A, 217, 13, 1900827 Wiley

129. M. Tavares, M. Bláhová, L. Sedláková, L. Elling, H. Pelantová et al. (2020)
High-Affinity N-(2-Hydroxypropyl)methacrylamide Copolymers with Tailored N-Acetyllactosamine Presentation Discriminate between Galectins
Biomacromol., 21, 2, 641-652 ACS Publications

130. C. Josenhans, J. Müthing, L. Elling, S. Bartfeld, H. Schmidt (2020)
How bacterial pathogens of the gastrointestinal tract use the mucosal glyco-code to harness mucus and microbiota: New ways to study an ancient bag of tricks
Int. J. Medic. Microbiol., 310, 2, 151392 ScienceDirect

131. M. Hoffmann, E. Gau, S. Braun, A. Pich, L .Elling (2020)
Enzymatic Synthesis of 2-(β-Galactosyl)-ethyl Methacrylate by β-Galactosidase from Pyrococcus woesei and Application for Glycopolymer Synthesis and Lectin Studies
Biomacromol., 21, 2, 974-987 ACS Publications


132. J. Gottschalk, M. Aßmann, J. Kuballa, L. Elling (2021)
Repetitive Synthesis of High-Molecular-Weight Hyaluronic Acid with Immobilized Enzyme Cascades
Chem. Sus. Chem., 15, 9, cssc.202101071 ChemistryEurope

133. J. Gottschalk, L. Blaschke, M. Aßmann, J. Kuballa, L. Elling (2021)
Integration of a Nucleoside triphosphate regeneration system in the one-pot synthesis of UDP-sugars and hyaluronic acid
ChemCatChem 13, 3074-3083. ChemistryEurope

134. V. Heine, M. Hovorková, M. Vlachová, M. Filipová, L. Bumba et al. (2021)
Immunoprotective neo-glycoproteins : Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3
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135. V. Heine, T. Kremers, N. Menzel, U. Schnakenberg, L. Elling (2021)
Electrochemical Impedance Spectroscopy Biosensor Enabling Kinetic Monitoring of Fucosyltransferase Activity
ACS Sensors, 6, 3, 1003-1011 ACS Publications


136. V. Heine, C. Dey, P. Bojarová, V. Křen, L. Elling (2022)
Methods of in vitro study of galectin-glycomaterial interaction
Biotechnol. Adv., 58, 107928 ScienceDirect

137. V. Heine, H. Pelantová, P. Bojarová, V. Křen, L. Elling (2022)
Targeted Fucosylation of Glycans with Engineered Bacterial Fucosyltransferase Variants
Chem. Cat. Chem., 14, 6, e202200037 ChemistryEurope

138. J. Gottschalk, M. Aßmann, J. Kuballa, L. Elling (2022)
Repetitive Synthesis of High-Molecular-Weight Hyaluronic Acid with Immobilized Enzyme Cascades
ChemSusChem 15, 9 ChemistryEurope

139. H. Frohnmeyer, S. Rueben, L. Elling (2022)
Gram-scale production of GDP-β-L-fucose with multi-enzyme cascades in a repetitive-batch mode
ChemCatChem ChemistryEurope