Glykane und Glykokonjugate
Glykane
Humane Milch-Oligosaccharide (HMOs)
Elling, L., Zervosen, A., Gutiérrez Gallego, R., Nieder, V., Malissard, M., Berger, E.G., Vliegenthart, J.F.G., Kamerling, J.P., 1999. UDP-N-acetyl-α-D-glucosamine as acceptor substrate of β-1,4-galactosyltransferase. Enzymatic synthesis of UDP-N-acetyllactosamine. Glycoconjugate J. 16, 327-336. https://doi.org/10.1023/A:1007039825505
Kamerke, C., Pattky, M., Huhn, C., Elling, L., 2012. Synthesis of UDP-activated Oligosaccharides with Commercial β-galactosidase from Bacillus circulans under Microwave Irradiation. J. Mol. Catal. B: Enzymatic 79, 27-34. https://doi.org/10.1016/j.molcatb.2012.04.003
Kamerke, C., Pattky, M., Huhn, C., Elling, L., 2013. Synthesis of Nucleotide-Activated Disaccharides with Recombinant β3-Galactosidase C from Bacillus circulans. J. Mol. Catal. B: Enzymatic 89, 73-81. https://doi.org/10.1016/j.molcatb.2012.12.014
Engels, L., Elling, L., 2014. WbgL: a novel bacterial α1,2-fucosyltransferase for the synthesis of 2′-fucosyllactose. Glycobiology 24, 170-178. https://doi.org/10.1093/glycob/cwt096
Fischöder, T., Cajic, S., Grote, V., Heinzler, R., Reichl, U., Franzreb, M., Rapp, E., Elling, L., 2019. Enzymatic Cascades for Tailored 13C6 and 15N Enriched Human Milk Oligosaccharides. Molecules 24, 3482. https://doi.org/10.3390/molecules24193482
Fischöder, T., Cajic, S., Reichl, U., Rapp, E., Elling, L., 2019. Enzymatic Cascade Synthesis Provides Novel Linear Human Milk Oligosaccharides as Reference Standards for xCGE-LIF Based High-Throughput Analysis. Biotechnol. J. 14, e1800305. https://doi.org/10.1002/biot.201800305
Glykokonjugate